Morning Session: Bioenergetics and metabolism of cancer cells
08:30 Course Registration
09:00 J. Cuezva The Bioenergetics signature of Cancer
09:45 R. Rossignol From bioenergetics to the metabolic regulation of carcinogenesis
metabolism and cancer
11:45 H. Simonnet Energy metabolism in proliferation and high nutrient demand
12:30 Poster Viewing
13:00 Lunch break
Afternoon Session
14:30 Concurrent Workshops
15:30 Coffee break
16:00 Concurrent Workshops
Thursday, November 4th
Morning Session: Impact of mitochondria and mitochondrial genes dysfunction on cancer cells
09:00 E. Gottlieb Metabolic sensors in cancer: from oxygen to amino acid sensing
09:45 G. Gasparre mtDNA mutations in the metabolic adaptation of cancer cells: learning from oncocytic tumors
10:30 Coffee break
11:00 A. J. Enriquez Respiratory chain defects and cancer development
11:45 K. Singh Epigenetic and Genetic Changes Induced by Mitochondrial Dysfunction and its role
Tumorigenesis
12:30 Poster Viewing
13:00 Lunch break
Afternoon Session
14:30 Concurrent Workshops
15:30 Coffee break
16:00 Concurrent Workshops
Friday, November 5th –
Morning Session: Mitochondria-related molecular pathways in cancer
09:00 M. Giorgio Mechanism of mitochondrial ROS production, signalling for cell
death and proliferation, side effects associated to mutagenesis and transformation
09:45 M.F. Di Renzo Cells lacking fumarase are protected from apoptosis through a HIF independent, AMPK dependent
mechanism
11:45 L. Alberghina Ras and mitochondria in cancer cells
12:30 Poster Viewing
13:00 Lunch break
Afternoon Session
14:30 Concurrent Workshops
15:30 Coffee break
16:00 Concurrent Workshops
17:00 Best Posters Ceremony
Saturday, November 6th
Morning Session: Mitochondria-related aspects of cancer research
09:00 M.N. Gadaleta Damage to mitochondrial DNA in aging and age-related diseases
09:45 M. Corral-Debrinski: Inducing heteroplasmy of mtDNA mutations to generate experimental models of mitochondrial
diseases. Cellular adaptations to OXPHOS defects in cancer
11.00 M. Attimonelli Bioinformatic approaches to study mtDNA variability in cancer
11:45 Course Director Conclusions
12:30 Lunch Break