Course | The course is intended for researchers directly involved in the statistical analysis of complex traits and disorders, and will primarily address the methods and applications of genetic association and linkage studies. It will consist of general lectures followed by hands-on computer-based workshops. It is an intermediate level course and some knowledge of genetics and statistics is a prerequisite. The topics covered are: Genetic epidemiology; Association studies; Data format, error checking, and quality control; HapMap data and other online resources; Linkage analysis; Special issues in Genome Wide Association Studies (GWAS); Quantative Trait Locus analysis (QTL); GxG and GxE; Power analysis in genetic studies; Analysis of Copy Number Variants (CNVs), Integrative genomic approaches for complex trait gene discovery, Sequence data and analysis of rare variants. |
Speakers | Lachlan Coin (London, UK) Fabrice Danjou (Cagliari, Italy) David Evans (Bristol, UK) Mario Falchi (London, UK) Paola Forabosco (Sassari, Italy) Harald Göring (San Antonio, USA) Claudia Specchia (Brescia, Italy) |
Programme | Monday, June 21st Morning session: 9:00: M.Devoto, Basics of genetic epidemiology 10:00: L. Coin, Basics of association studies 11:00: Coffee break 11:30: P. Forabosco, Workshop 1: Data format, error checking and quality control 13:00: Lunch break Afternoon session: 14:00: D. Evans, Workshop 2: HapMap data and other online resources 15:30: Coffee break 16:00: C. Specchia, Workshop 3: Association studies (1): Candidate gene analysis Tuesday, June 22nd Morning session: 9:00: M. Devoto, Linkage analysis 10:00: D. Evans, Special issues in Genome Wide Association Studies 11:00: Coffee break 11:30: M. Devoto, Workshop 1: Linkage analysis 13:00: Lunch break Afternoon session: 14:00: D. Evans, Workshop 2: Association studies (2): GWAS analysis 15:30: Coffee break 16:00: F. Danjou, Workshop 3: Association studies (3): GWAS results interpretation Wednesday, June 23rd Morning session: 9:00: H. Göring, Quantitative Trait Locus analysis 10:00: L. Coin, Analysis of Copy Number Variants 11:00: Coffee break 11:30: M. Falchi, Workshop 1: QTL analysis 13:00: Lunch break Afternoon session: 14:00: L. Coin, Workshop 2: Copy Number Variants 15:30: Coffee break 16:00: P. Forabosco, Workshop 3: Power analysis in genetic studies Thursday, June 24th Morning session: 9:00: M. Falchi, Sequence data and analysis of rare variants 10:00: H. Göring, Integrative genomic approaches for complex trait gene discovery 11:00: Coffee break 11:30: Open session with questions from students 13:00: Lunch break Departure after lunch |