The course will provide detailed information on the tools useful for the study of human genomic evolution.  High-throughput, large scale genotyping, using both microarrays and massive sequencing to survey both SNPs and CNV will bring increasing power to studies of genomic diversity in the near future. Bioinformatics is an essential tool in studies of human genomic evolution. Workshops will show how bioinformatic tools can be used to analyze SNP and CNV diversity within an evolutionary framework. The course will be of interest to researchers, graduate students and post-docs interested in genome biology and human evolution. It will also provide a venue for rapid exposure to the "state of the art" for investigators contemplating studies, or the utilization of tools, in this field.

D. Luiselli ( Bologna, Italy)

D. Pettener (Bologna, Italy)

M. Rocchi (Bari, Italy)

R. Stanyon ( Florence, Italy)

G. Barbujani (Ferrara, Italy)

F. Calafell (Barcelona, Spain)

L.L. Cavalli Sforza ( Stanford, UK)

C. Guardiano (Reggio Emilia, Italy)

J. Krause (Leipzig, Germany)

D. Pettener (Bologna, Italy)

A. Qasim (Cambridge, UK)

M. Rocchi ( Bari, Italy)

R. Stanyon (Florence, Italy)

M. Stoneking (Leipzig Germany)

C. Tyler- Smith ( Cambridge, UK)

S. Wells (Cornell, USA)

Monday, May 17^th

Morning session: Human genome structure and variability

9:00 Course Registration

9:15- 9:45: L.L. Cavalli Sforza, Course Introduction

9:45-10:30: R. Stanyon, Origin of the Human Genome

10:30-11:00: Coffee Break

11:00-11:45 M. Rocchi, Human genome plasticity.

11:45-12:30: J. Krause, Neandertal perspective on Human Evolution

12:30-13:15: G. Barbujani, Inferring demographic processes from comparisons of ancient and modern DNAs

13:15- 13:30: Questions from students on morning lectures

13:30: Lunch Break

Afternoon Session: Concurrent Workshops 15:00 – 18.00

Tuesday, May 18th

Morning Session: Theory and Models of Evolutionary Analysis

9:00 –09:45: C. Tyler-Smith, Natural Selection in humans

9:45-10:30 : M. Stoneking, Next-generation sequencing of complete mtDNA genomes

10:30-11:00 Coffee Break

11:00-11.45: S. Wells , Tracking human migration: Insights from the Genographic Project

11:45 –12:30: F. Calafell,  Incorporating recombination into human population genetics

12:30-13:00: Questions from students on morning lectures

13:00 Lunch Break

Afternoon Session: Workshops 15:00 – 18:00 Concurrent Workshops

Wednesday, May 19th
Morning Session: Demography and Culture

9:00 –09:45: P. Longobardi, Linguistic methods and reconstruction of the past

9:45- 10:30 C. Guardiano,  New Linguistic methods and population genetics

10:30 –11:00 Coffee Break

11:00-11:45 D. Pettener, Sampling stragety in human population genetics: a biodemographic approach.

11:45 –12:30 A. Qasim,  Genetic variation in Pakistan: Influence of geography, ethnicity and language

12:30-13:15  t.b.d 

13:15-13:30 Questions from students on morning lectures

13:30 Lunch break

 Departure