From | 2011-04-11 | |
To | 2011-04-13 | |
Course |
Cognitive disorders make a major impact on modern society, and it is well established that genetic factors play a substantive role. In recent years dramatic advances in molecular biology, human genomics and model systems have not only accelerated the identification of key susceptibility genes, but also yielded exciting new insights into the aetiological mechanisms underlying these disorders. The course will provide an overview of the state-of-the-art in the field, with lectures from the leading experts studying intellectual disability, autism spectrum disorders, and impairments in speech, language and reading. These researchers are dissecting the critical neurogenetic pathways that go awry through diverse approaches, analysing genes involved in Mendelian disorders, chromosomal rearrangement syndromes, and complex multifactorial traits. Topics of discussion will include the use of cutting-edge methods to pinpoint risk genes; the functional characterisation of gene networks in tissue culture systems and animal models; potential roles of neuronal migration, synapse biology and neural plasticity; and consideration of genetically-mediated overlaps between distinct cognitive disorders. | |
Venue | Bologna - Centro Universitario EuroMediterraneo di Ronzano | |
Directors | T. Bourgeron (Paris, France) S. Fisher (Oxford,UK) Co-directors:
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Speakers | T. Boekers (Ulm, Germany) T. Bourgeron (Paris, France) J. Chelly (Paris, France) S. Fisher (Oxford, UK & Nijmegen, the Netherlands) J. Kere (Huddinge, Sweden) D. Newbury (Oxford, Uk) L. Osborne (Toronto, Canada) D. Pinto (Toronto, Canada) J. Sutcliffe (Nashville, Usa) H. van Bokhoven (Nijmegen, The Netherlands) O. Zuffardi (Pavia, Italy) A. Schenck (Nijmegen, The Netherlands) | |
Programme | Monday, 11 April , 2011
11.30 D. Pinto From CNVs to pathways in Autism Spectrum Disorders 13.15 Lunch break Morning: plenary lectures: SPEECH/LANGUAGE/READING 11.00 Coffee break 11.30 J. Kere Molecular biology of dyslexia 13.15 Lunch break 10.15 O. Zuffardi Genome-wide array in mental retardation 11.30 J. Chelly Signaling pathways and pathophysiological mechanisms underlying intellectual disability 13.00 ECM Test Departure |